BDBM82258 CAS_114798-26-4::Losartan::NSC_3961
SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InChI Key InChIKey=PSIFNNKUMBGKDQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 82258
Affinity DataKi: 5.70nMAssay Description:Binding against Angiotensin II receptor in a radioligand binding assay using [125I]-Sar1-Ile8 angiotensin-II as radioligand in rat adrenal cortical m...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Tested for inhibitory concentration against AT1 receptor binding affinity in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against binding of [125I]angiotensin II to rat liver expressing Angiotensin II receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory activity against rat Angiotensin II receptor, type 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration against [125 I]Ang II binding to rat pituitary membranes Angiotensin II receptor type 1 without 0.2% bovine serum albuminMore data for this Ligand-Target Pair